货号：PMK0914
Carbocyanine Dyes Amine-Reactive:Cyanine dyes are a series of reactive fluorescent dyes that are widely used for labeling peptides, proteins, nucleotides and nucleic acids. Cyanine dyes are a single family of bright fluorescent signals with good water-solubility. Unlike fluoresceins and hydroxycoumarins, their excitations and emissions are pH-independent. Among the cyanine dyes, Cyanine 3 dyes have fluorescence enhanced upon conjugating to proteins while other cyanine have fluorescence reduced due to the quenching effect of electron-rich amino acids (such as Trp, His and Tyr etc) in proteins.
In general, the Cyanine dyes have the following features:Good water solubility enables labeling reactions conveniently run in aquesous media without using organic solvents (such as DMF or DMSO) as co-solvent.Low non-specific binding of resultant conjugates facilitate the assay development.
